reactions, all of which are carried out with close attention to
safety and consistency.
CROSS-COUPLING REACTIONS (SUZUKI, SONOGASHIRA)
SYNTHESIS OF ENANTIOPURE COMPOUNDS
Asymmetric synthesis | Optical resolutions
REACTIONS WITH ANHYDROUS ACIDIC AND BASIC GASES
OXIDATION/REDUCTION REACTIONS
fully-certified cGMP Biazzi
hydrogenation equipment, a
leading, highly efficient, patented
technology that delivers clean
reaction profiles.
The pilot scale Biazzi plant is a 100 L reactor capable of withstanding pressures of up to 40 bar and which is routinely utilised in the production of small-scale high-value products. All equipment has been designed, installed and maintained in accordance with cGMP.
plant, Amino Chemicals also
features a small-scale production
plant dedicated to high-value
products of smaller batch size.
The SPP also doubles as a pilot plant when industrialisation feasibility studies for new and existing projects are required. Notable features include; variable reactor capacity and layout (0.25 – 1 m3), dedicated thermal oil heating/cooling system, boxed centrifuges for different batch sizes (SS/Halar, ϕ = 500 mm/800 mm).
Technologies include; clean-rooms supplied with filtered air by HVAC system, stainless steel driers (1 – 2.4 m3) with dedicated vacuum systems up to full vacuum, boxed centrifuges (stainless steel and halar) with HVAC air filtration systems, blending and granulation equipment, milling and sieving equipment, jet mill micronisation (small and large scale).
Overview
- REACTOR VOLUME
About 43 m3 (range 0.25-10 m3, SS/glass lined/hastelloy) - OPERATING TEMPERATURE RANGE
-10°C to +180°C - PRESSURE RATING
From full vacuum up to 6 bar - SPECIFIC TECHNOLOGIES
Heterogeneous hydrogenation (up to 40 bar), filter drier (500 L) - PROCESS WATER PLANT
PROCESS WATER PLANT - FINISHING AREAS
Centrifuges (SS/halar lined), driers (SS), blender and mill in clean-rooms with filtered air by HVAC system - SMALL SCALE PRODUCTION PLANT
Doubles as a pilot plant for project scale-up studies
Glass-lined and stainless steel reactors (from 250 lt to 1000 lt)
Centrifuges enclosed in a dedicated clean room
